
FOXO4 (10mg)
$299.99
FOXO4-DRI is a D-retro-inverso peptide studied in cellular senescence and p53-interaction research models. Lyophilized powder for laboratory research use only.
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U.S. Third-Party Tested
COA available for each product
Independently Verified. Every Batch
Every Aurevena product is sent to an independent, accredited third-party laboratory before it is offered for sale. Certificates of Analysis confirm compound identity, purity percentage, and the absence of harmful contaminants.
COAs are published by lot number so researchers can verify the exact product they receive. We do not sell any product that does not clear our purity threshold.
- Compound identity (HPLC / MS verification)
- Purity percentage (target ≥ 99%)
- Absence of heavy metals
- Lot-number traceability
FOXO4 (10mg)
10mg
- Description
- Compound Info
- Research Overview
Description
FOXO4-DRI is a D-retro-inverso peptide designed to interfere with the interaction between the transcription factor FOXO4 and the tumor-suppressor protein p53, making it a prominent tool compound in cellular-senescence research. Laboratory investigators study FOXO4-DRI for its role in disrupting FOXO4-p53 binding, modeling senescent-cell signaling, and probing senolytic mechanisms in vitro and in preclinical systems. Supplied for in-vitro and laboratory research only — not for human or veterinary use.
| Compound Class | Synthetic retro-inverso D-amino acid peptide (FOXO4-DRI) |
|---|---|
| CAS Number | Not assigned |
| Molecular Formula | Variable depending on synthesis |
| Molecular Weight | Approximately 2.9 kDa |
| Sequence | Retro-inverso D-amino acid peptide derived from FOXO4-p53 binding interface (full sequence in scientific literature) |
| Appearance | White to off-white lyophilized powder |
Research Overview
Storage
IMPORTANT RESEARCH NOTICE
Not for human consumption.
This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease. All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims. By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.
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Sources & References
Peer-reviewed research
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI
Research FAQ
Compound and research-use information
What is FOXO4-DRI?
FOXO4-DRI is a synthetic D-retro-inverso peptide designed to disrupt the FOXO4-p53 protein interaction in research models. It is supplied as a research chemical.
What is FOXO4-DRI studied for in the research setting?
FOXO4-DRI is used in vitro and in preclinical cellular-senescence research to study the FOXO4-p53 interaction and senescent-cell biology. It is a mechanistic research tool used in senescence and cell-aging models.
What form is Aurevena's FOXO4-DRI supplied in?
FOXO4-DRI is supplied as a lyophilized (freeze-dried) powder. Every batch is tested by independent, accredited U.S. laboratories for purity and identity, with the Certificate of Analysis published on this product page. Store lyophilized peptide cold and protected from light, and avoid repeated freeze-thaw cycles.
Is FOXO4-DRI intended for human use?
No. FOXO4-DRI is sold by Aurevena strictly for laboratory and research use only. It is not a drug, dietary supplement, cosmetic, or medical device, and is not intended for human or veterinary use, consumption, or for the diagnosis, treatment, cure, or prevention of any disease.




