$57.99

LL-37 is a human cathelicidin antimicrobial peptide studied in innate-immunity and host-defense research models. Lyophilized powder for laboratory research use only.

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COA available for each product

Independently Verified. Every Batch

Every Aurevena product is sent to an independent, accredited third-party laboratory before it is offered for sale. Certificates of Analysis confirm compound identity, purity percentage, and the absence of harmful contaminants.

COAs are published by lot number so researchers can verify the exact product they receive. We do not sell any product that does not clear our purity threshold.

  • Compound identity (HPLC / MS verification)
  • Purity percentage (target ≥ 99%)
  • Absence of heavy metals
  • Lot-number traceability
CERTIFICATE OF ANALYSIS

LL37 (5mg)

5mg

PURITY 99.80%%
ASSAY 5.79mg
IDENTITY Confirmed
HEAVY METALS <50 ppb
TAMC 0 CFU
TYMC 0 CFU
BATCH/LOT LL375202026
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Description

LL-37 is the only human cathelicidin-derived antimicrobial peptide and a widely used tool compound in innate-immunity research. Laboratory investigators study LL-37 for its membrane-interacting antimicrobial activity, immunomodulatory signaling, chemotactic effects on immune cells, and its role in host-defense and wound-environment models in vitro and in preclinical systems. It is examined for interactions with bacterial membranes, biofilm models, and Toll-like receptor signaling. Supplied for in-vitro and laboratory research only — not for human or veterinary use.

Compound ClassSynthetic 37-amino acid cathelicidin-derived antimicrobial peptide (human cathelicidin LL-37)
CAS Number154947-66-7
Molecular FormulaC205H340N60O53
Molecular WeightApproximately 4493.33 g/mol
SequenceLeu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser
AppearanceWhite to off-white lyophilized powder

Research Overview

Used in in vitro and preclinical research relating to host defense peptide chemistry and antimicrobial peptide structure-activity studies.

Storage

Store unreconstituted vials refrigerated at 2-8°C and long-term at -20°C; once reconstituted, store at 2-8°C and use within 30 days.

IMPORTANT RESEARCH NOTICE

Not for human consumption.

This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

Frequently Asked Questions

Lyophilized (powder) peptides should be stored at -20°C for long-term storage or 2-8°C (refrigerator) for short-term. Always protect from light and avoid repeated freeze-thaw cycles.
We offer damage protection on every order. If your product arrives damaged in transit, contact us with photos for a one-time replacement. All claims require photo evidence and are subject to review. One replacement per customer per order. Reconstituted products are not eligible. We do not offer refunds for change of mind or misuse.
Yes, every batch is tested by independent, accredited U.S. laboratories for purity verification and Mass Spectrometry for identity confirmation. Test results are published on each product page as Certificates of Analysis (CoA).
Orders are processed within 1-2 business days. Standard shipping typically arrives within 3-5 business days from fulfillment. Express and overnight options are available at checkout. Every order includes free shipment protection.
Currently, we ship within the United States only. We're working on expanding our shipping capabilities to serve researchers worldwide.
Orders can be modified or canceled within 5 min of placement. After this window, orders enter processing and cannot be changed. Contact hello@aurevenaresearch.com immediately if you need to make changes.
We offer damage protection on every order. If your product arrives damaged in transit, contact us with photos for a one-time replacement. All claims require photo evidence and are subject to review. One replacement per customer per order. Reconstituted products are not eligible. We do not offer refunds for change of mind or misuse.

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Sources & References

Peer-reviewed research

IMMUNE RESEARCHLL37 (5mg)3 SOURCES
Pharmacol Rep

LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity

VOL 68(4):802-808 · PMID 27117377 · DOI 10.1016/j.pharep.2016.03.015
Fabisiak A, Murawska N, Fichna J · 2016
Front Immunol

Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis

VOL 13:880961 · PMID 35634307 · DOI 10.3389/fimmu.2022.880961
Aloul KM, Nielsen JE, Defensor EB, et al. · 2022
Int J Mol Sci

Therapeutic Potential of Cathelicidin Peptide LL-37, an Antimicrobial Agent, in a Murine Sepsis Model

VOL 21(17) · PMID 32825174 · DOI 10.3390/ijms21175973
Nagaoka I, Tamura H, Reich J · 2020

Research FAQ

Compound and research-use information

What is LL-37?

LL-37 is the naturally occurring human cathelicidin antimicrobial peptide (37 residues). It is supplied for laboratory research use.

What is LL-37 studied for in the research setting?

LL-37 is studied in vitro and in preclinical models for research into host-defense (antimicrobial) activity, immune modulation, and membrane interactions. It is used as a reference antimicrobial peptide in immunology and microbiology research.

What form is Aurevena's LL-37 supplied in?

LL-37 is supplied as a lyophilized (freeze-dried) powder. Every batch is tested by independent, accredited U.S. laboratories for purity and identity, with the Certificate of Analysis published on this product page. Store lyophilized peptide cold and protected from light, and avoid repeated freeze-thaw cycles.

Is LL-37 intended for human use?

No. LL-37 is sold by Aurevena strictly for laboratory and research use only. It is not a drug, dietary supplement, cosmetic, or medical device, and is not intended for human or veterinary use, consumption, or for the diagnosis, treatment, cure, or prevention of any disease.