ACE-031 (1mg)

$173.99

ACE-031 is a soluble activin receptor type IIB construct studied in myostatin-pathway and muscle research models. Lyophilized powder for laboratory research use only.

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COA available for each product

Independently Verified. Every Batch

Every Aurevena product is sent to an independent, accredited third-party laboratory before it is offered for sale. Certificates of Analysis confirm compound identity, purity percentage, and the absence of harmful contaminants.

COAs are published by lot number so researchers can verify the exact product they receive. We do not sell any product that does not clear our purity threshold.

  • Compound identity (HPLC / MS verification)
  • Purity percentage (target ≥ 99%)
  • Absence of heavy metals
  • Lot-number traceability
CERTIFICATE OF ANALYSIS

ACE-031 (1mg)

1mg

PURITY 99.70%%
ASSAY 1.03mg
IDENTITY Confirmed
HEAVY METALS <10 ppb
TAMC 0 CFU
TYMC 0 CFU
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Description

ACE-031 is a research construct based on a soluble form of the activin receptor type IIB (ActRIIB) fused to an Fc domain, designed to act as a decoy receptor that binds myostatin and related ligands. It is used as a tool compound in muscle-regulation research. Supplied for in-vitro and laboratory research only — not for human or veterinary use.

Compound ClassRecombinant fusion protein (soluble activin receptor type IIB linked to human IgG1 Fc domain)
CAS NumberNot assigned (recombinant biologic)
Molecular FormulaRecombinant fusion protein, variable
Molecular WeightApproximately 80 kDa (dimeric)
SequenceExtracellular domain of human ActRIIB fused to human IgG1 Fc
AppearanceWhite to off-white lyophilized powder

Research Overview

Used in in vitro and preclinical research relating to TGF-beta/activin receptor chemistry and myostatin/activin pathway studies.

Storage

Store unreconstituted vials refrigerated at 2-8°C and long-term at -20°C; once reconstituted, store at 2-8°C and use within 30 days.

IMPORTANT RESEARCH NOTICE

Not for human consumption.

This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

Frequently Asked Questions

Lyophilized (powder) peptides should be stored at -20°C for long-term storage or 2-8°C (refrigerator) for short-term. Always protect from light and avoid repeated freeze-thaw cycles.
We offer damage protection on every order. If your product arrives damaged in transit, contact us with photos for a one-time replacement. All claims require photo evidence and are subject to review. One replacement per customer per order. Reconstituted products are not eligible. We do not offer refunds for change of mind or misuse.
Yes, every batch is tested by independent, accredited U.S. laboratories for purity verification and Mass Spectrometry for identity confirmation. Test results are published on each product page as Certificates of Analysis (CoA).
Orders are processed within 1-2 business days. Standard shipping typically arrives within 3-5 business days from fulfillment. Express and overnight options are available at checkout. Every order includes free shipment protection.
Currently, we ship within the United States only. We're working on expanding our shipping capabilities to serve researchers worldwide.
Orders can be modified or canceled within 5 min of placement. After this window, orders enter processing and cannot be changed. Contact hello@aurevenaresearch.com immediately if you need to make changes.
We offer damage protection on every order. If your product arrives damaged in transit, contact us with photos for a one-time replacement. All claims require photo evidence and are subject to review. One replacement per customer per order. Reconstituted products are not eligible. We do not offer refunds for change of mind or misuse.

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Sources & References

Peer-reviewed research

SECRETAGOGUE RESEARCHACE-031 (1mg)3 SOURCES
PLoS One

ACE-031, a soluble activin type IIB receptor, increases muscle mass and strength in the common marmoset

VOL 21(2):e0342666 · PMID 41686840 · DOI 10.1371/journal.pone.0342666
Cadena SM, Bogdanovich S, Khurana TS, et al. · 2026
bioRxiv

ACE-031, a Soluble Activin Type IIB Receptor, Increases Muscle Mass and Strength in the Common Marmoset (Callithrix jacchus)

PMID 41256654 · DOI 10.1101/2025.10.01.679778
Cadena SM, Bogdanovich S, Khurana TS, et al. · 2025
Muscle Nerve

Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy: Results of a randomized, placebo-controlled clinical trial

VOL 55(4):458-464 · PMID 27462804 · DOI 10.1002/mus.25268
Campbell C, McMillan HJ, Mah JK, et al. · 2017

Research FAQ

Compound and research-use information

What is ACE-031?

ACE-031 is a soluble fusion protein based on the activin receptor type IIB (ActRIIB) that acts as a decoy receptor for myostatin and related ligands in research models. It is supplied for laboratory research.

What is ACE-031 studied for in the research setting?

In preclinical research ACE-031 is used to study inhibition of the myostatin / activin signaling pathway by sequestering ActRIIB ligands, in cell and animal muscle-biology models. It is a mechanistic research tool only.

What form is Aurevena's ACE-031 supplied in?

ACE-031 is supplied as a lyophilized (freeze-dried) powder. Every batch is tested by independent, accredited U.S. laboratories for purity and identity, with the Certificate of Analysis published on this product page. Store lyophilized peptide cold and protected from light, and avoid repeated freeze-thaw cycles.

Is ACE-031 intended for human use?

No. ACE-031 is sold by Aurevena strictly for laboratory and research use only. It is not a drug, dietary supplement, cosmetic, or medical device, and is not intended for human or veterinary use, consumption, or for the diagnosis, treatment, cure, or prevention of any disease.